Bromoacetyl bromide

CAS Number

598-21-0

Molecular Formula

C2H2Br2O

Also known as:

alpha-Bromoacetyl bromide, 2-Bromoacetyl bromide, Bromoacetic acid bromide.

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Product Description

Product Introduction

Bromoacetyl bromide (CAS 598-21-0) is an organic compound with the molecular formula C2H2Br2O. It is a colorless to pale yellow, heavy, fuming liquid with a sharp, pungent odor. As a bifunctional molecule containing both an acyl bromide and an alpha-bromo group, Bromoacetyl bromide (CAS 598-21-0) is an extremely powerful and versatile synthetic tool. It is primarily used to introduce the bromoacetyl moiety into organic molecules, serving as a critical building block for the synthesis of various active pharmaceutical ingredients (APIs) and specialty chemicals.

Product Selling Points

  • High Reactivity: Dual-functional groups allow for simultaneous or sequential acylation and substitution reactions.

  • High Assay (≥ 98.0%): Chemfine ensures high-quality production with minimal hydrolysis products or free bromine.

  • Strict Isomer Control: Controlled manufacturing process to maintain high yield in downstream pharmaceutical synthesis.

  • Low Impurity Profile: Minimized trace metal and organic impurities, ensuring compatibility with sensitive API production.

  • Specialized Packaging: Shipped in high-integrity, corrosion-resistant containers to ensure safety and product stability.

  • Expert Handling: Full technical and safety documentation provided for this highly corrosive and lachrymatory material.


Applications

Pharmaceutical Synthesis A vital intermediate for the synthesis of various drugs, including certain types of analgesics, antibiotics, and cardiovascular medications. It is often used to build heterocyclic rings.

Agrochemicals Used in the production of specialized herbicides and fungicides where a bromoacetyl group is required for biological activity.

Fine Chemical Synthesis Serves as an important reagent for the preparation of alpha-bromoesters, amides, and other bromoacetyl derivatives.

Peptide Synthesis Used in specialized peptide chemistry and protein modification as a cross-linking or derivatizing agent.

Chemical Research A common reagent in organic laboratories for the functionalization of alcohols, amines, and thiols.


Packaging

Standard industrial packaging options for Bromoacetyl bromide include:

  • 25kg or 50kg specialized corrosion-resistant plastic drums.

  • 250kg glass-lined or high-quality PVDF-lined steel drums for large-scale industrial use.

  • Smaller high-integrity bottles for laboratory-scale requirements.

  • All packaging is strictly UN-certified for corrosive and toxic liquids.


Storage

Bromoacetyl bromide is a highly corrosive, moisture-sensitive, and lachrymatory liquid. It must be stored in a cool, dry, and well-ventilated dedicated chemical warehouse. Keep containers tightly sealed and protected from moisture (it reacts violently with water to form HBr). Store away from strong bases, alcohols, and oxidizing agents. It is recommended to store under an inert gas (Nitrogen) blanket to maintain purity. Properly stored, it has a shelf life of 12-18 months.

Technical Parameters

Parameter Value
Appearance Colorless to Yellow Liquid
Assay (GC/Titration) ≥ 98.00%
Free Bromine (Br2) ≤ 0.50%
Sulfate (SO4) ≤ 0.05%
Iron (Fe) ≤ 0.005%
Residue on Ignition ≤ 0.10%

Applications

Plasticizers/Dispersing Agents

Quick Information

EINECS 209-923-5
Molecular Weight 201.84 g/mol

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