Benzyl chloride

CAS Number

100-44-7

Molecular Formula

C₇H₇Cl

Also known as:

Benzyl chloride; α-Chlorotoluene methylene chloride; Benzyl chloride (nomenclature: C₆H₅CH₂Cl)

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Product Description

Benzyl chloride CAS 100-44-7
Benzyl chloride is a primary benzylic chloride supplied as a colorless to pale yellow liquid. It is used as an alkylating reagent and intermediate in the manufacture of benzyl derivatives, benzyl ethers, pharmaceuticals, agrochemicals, benzyl esters and specialty solvents. Benzyl chloride is reactive toward nucleophiles and hydrolyzes slowly in water; handle under controlled conditions with appropriate personal protection and engineering controls.

Applications

  • Alkylation intermediate
    Used as a benzylating agent for O-, N- and S-benzylation in the synthesis of pharmaceuticals, agrochemical intermediates and fine chemicals.
  • Benzyl ether / ester synthesis
    Employed to prepare benzyl-protected alcohols and benzyl esters in multi-step organic syntheses and protective-group chemistry.
  • Solvent and extraction medium
    Used selectively as an organic solvent in specialty extractions and reaction media where benzylic reactivity is acceptable.
  • Fragrance and flavor intermediate
    Used as a chemical building block in the synthesis of benzyl-containing aroma compounds (use subject to regulatory approval for food/flavor applications).
  • Analytical reagent and standard
    Supplied as a reference standard for GC/HPLC method development and quality control for benzylic chlorides and related chemistries.

Technical Parameters

Parameter Value
Assay ≥ 99.0
Appearance Colorless to pale yellow clear liquid
Melting point (°C) −15.0
Boiling point (°C, 1 atm) 179.0
Density (g·mL⁻¹ at 20 °C) 1.103
Refractive index (n²⁰_D) 1.5420
Refractive index (n²⁰_D) 1.5420
Water solubility (g·L⁻¹ at 20 °C) 0.9
Vapor pressure (kPa at 20 °C) 1.33
Flash point (°C, closed cup) 33

Applications

Plasticizers/Dispersing Agents

Quick Information

EINECS 202-851-5
Molecular Weight 126.58 g/mol

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