Product Introduction
Acetyl Chloride (CAS 75-36-5), also known as Ethanoyl Chloride, is a highly reactive organic compound belonging to the acyl halide family. It is a colorless, fuming liquid with a pungent, suffocating odor. In the chemical industry, it is one of the most important acetylating agents available. It reacts vigorously with water, alcohols, and amines, making it an indispensable tool for introducing the acetyl group into organic molecules. Its high reactivity makes it a preferred choice over acetic anhydride in many specialized pharmaceutical and fine chemical syntheses.
Product Selling Points
1. Exceptional Reactivity for Fast Synthesis
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Advantage: Higher acylating power compared to acetic acid or acetic anhydride.
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Benefit: Shorter Reaction Times: Enables rapid conversion in Friedel-Crafts hospitalizations and esterification, increasing factory throughput and lowering energy costs.
2. High Assay for Sensitive Reactions
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Advantage: Maintained at ≥ 99.0% purity with minimal free acid content.
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Benefit: Consistent Yields: Reduces the formation of complex side products, making it ideal for the synthesis of sensitive pharmaceutical active ingredients (APIs).
3. Versatile Intermediate for Global Industries
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Advantage: Acts as a universal building block for acetyl groups in multiple chemical sectors.
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Benefit: Wide Application Range: From common painkillers like Acetaminophen to advanced liquid crystal materials and high-performance dyes.
SEO Optimization
SEO Title: Acetyl Chloride | CAS 75-36-5 | High Purity Acetylating Agent
SEO Description: Premium Acetyl Chloride (CAS 75-36-5) by Chemfine. Essential reagent for pharmaceutical synthesis, dyes, and agrochemicals. High reactivity and stable supply.
SEO Keywords: 75-36-5, Acetyl Chloride, Ethanoyl Chloride, Acetylation Reagent, Pharmaceutical Intermediate, Dye Intermediate, Chemfine
Price: $1.50 – $2.80 / kg (Note: Prices fluctuate based on glacial acetic acid and chlorinating agent costs; please contact our sales team for a real-time quotation).
MOQ: 200 kg (Standard UN-certified plastic-lined steel drums).
Google Snippet:
Looking for high-purity Acetyl Chloride? Chemfine supplies CAS 75-36-5 with an assay of ≥ 99.0%. As a highly reactive acyl halide, it is a key building block for the synthesis of aspirin, acetaphenone, and various crop protection chemicals. Our product is strictly moisture-controlled to ensure potency. Contact us for bulk pricing, COA, and specialized hazardous material logistics.
Marketing Titles (Alibaba Edition)
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High Purity 99% Acetyl Chloride CAS 75-36-5 | Critical Pharmaceutical Reagent
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Factory Supply Ethanoyl Chloride | Powerful Acetylating Agent for Fine Chemicals
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99.0% Min Acetyl Chloride | Reliable Intermediate for Dyes, Pesticides & Organic Synthesis
Product Introduction
Acetyl Chloride (CAS 75-36-5), also known as Ethanoyl Chloride, is a highly reactive organic compound belonging to the acyl halide family. It is a colorless, fuming liquid with a pungent, suffocating odor. In the chemical industry, it is one of the most important acetylating agents available. It reacts vigorously with water, alcohols, and amines, making it an indispensable tool for introducing the acetyl group into organic molecules. Its high reactivity makes it a preferred choice over acetic anhydride in many specialized pharmaceutical and fine chemical syntheses.
产品卖点 (Product Selling Points)
1. Exceptional Reactivity for Fast Synthesis
-
Advantage: Higher acylating power compared to acetic acid or acetic anhydride.
-
Benefit: Shorter Reaction Times: Enables rapid conversion in Friedel-Crafts hospitalizations and esterification, increasing factory throughput and lowering energy costs.
2. High Assay for Sensitive Reactions
-
Advantage: Maintained at ≥ 99.0% purity with minimal free acid content.
-
Benefit: Consistent Yields: Reduces the formation of complex side products, making it ideal for the synthesis of sensitive pharmaceutical active ingredients (APIs).
3. Versatile Intermediate for Global Industries
-
Advantage: Acts as a universal building block for acetyl groups in multiple chemical sectors.
-
Benefit: Wide Application Range: From common painkillers like Acetaminophen to advanced liquid crystal materials and high-performance dyes.
Applications
Pharmaceutical Manufacturing
A core reagent for the production of analgesics (Aspirin, Acetaminophen) and various antibiotics and vitamins.
Agrochemical Synthesis
Used in the synthesis of several types of herbicides and insecticides by introducing the acetyl functional group.
Dyes & Pigments
Serves as an intermediate in the production of acetoacetanilide and other dye precursors for the textile industry.
Organic Synthesis
Widely used in Friedel-Crafts acylation reactions to produce aromatic ketones (like acetophenone) and as a catalyst in certain chlorination processes.
Packaging & Storage
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Packaging: 200kg UN-certified plastic-lined steel drums; 1000kg IBC tanks (moisture-sealed).
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Storage: Store in a cool, dry, and well-ventilated fireproof area. Crucial: Must be kept strictly away from moisture, water, and alcohols as it reacts violently to release toxic hydrogen chloride (HCl) gas. Containers must be hermetically sealed and stored under a dry nitrogen blanket.
Synonyms
Ethanoyl chloride; Acetic acid chloride; Acetic chloride.
Matching Materials
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Glacial Acetic Acid (CAS 64-19-7) —— Common precursor for production
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Phosphorus Trichloride (CAS 7719-12-2) —— Chlorinating agent used in its manufacture
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Aluminum Chloride (CAS 7446-70-0) —— Catalyst used with Acetyl Chloride in Friedel-Crafts reactions
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Aniline (CAS 62-53-3) —— Reactant used with Acetyl Chloride to produce acetanilide
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Ethanol (CAS 64-17-5) —— Warning: Reacts violently to produce Ethyl Acetate
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Salicylic Acid (CAS 69-72-7) —— Reactant used to synthesize Aspirin
FAQ
Q: Why does Acetyl Chloride “fume” when the bottle is opened?
A: It reacts instantly with moisture in the air to produce hydrogen chloride (HCl) gas, which appears as white acidic fumes. This is a sign of high reactivity and purity.
Q: Can it be stored in standard plastic containers?
A: No. It is highly corrosive and can penetrate many plastics. We use specialized UN-certified, plastic-lined steel drums designed specifically for corrosive and flammable acyl halides.
Q: What is the most critical safety precaution?
A: Always handle in a high-efficiency fume hood and never allow it to come into contact with water. In case of a spill, do not use water to wash it; use dry sand or specialized chemical absorbents.
Q: Is it different from Acetic Anhydride?
A: Yes, Acetyl Chloride is much more reactive. While both introduce acetyl groups, Acetyl Chloride is often required for substrates that are less nucleophilic or when faster reaction rates are needed.
Q: How do you manage its shipment as a hazardous material?
A: It is classified as UN 1717 (Class 3, Sub-risk 8). We provide full IMO-compliant documentation and use reinforced packaging to ensure safe global transit.
