Product Introduction
2,2,2-Trifluoroethanol, commonly known by its abbreviation TFE (CAS 75-89-8), is a clear, colorless, and water-miscible liquid with an alcohol-like odor. Due to the high electronegativity of the three fluorine atoms, 2,2,2-Trifluoroethanol (CAS 75-89-8) possesses a significantly more acidic hydroxyl group compared to ethanol. This unique chemical profile makes TFE an extraordinary solvent for dissolving proteins and specialized polymers that are otherwise difficult to solubilize. It is highly valued in the fine chemical industry as a versatile building block, facilitating the introduction of trifluoroethyl groups into a wide variety of organic molecules.
Applications
Pharmaceutical Intermediate This product is a critical building block in the synthesis of various active pharmaceutical ingredients (APIs), including inhaled anesthetics and agents used for treating cardiovascular conditions.
Protein and Peptide Solvent TFE is widely used in biochemical research as a solvent that stabilizes the alpha-helical structures of proteins and peptides, making it indispensable for NMR spectroscopy and folding studies.
High-Performance Polymer Solvent It acts as a specialized solvent and reaction medium for the production of polyamides, polyesters, and other technical plastics that require high-polarity environments for synthesis.
Working Fluid for Rankine Cycles Due to its favorable thermodynamic properties and stability, it is utilized as a working fluid in Organic Rankine Cycle (ORC) systems for waste heat recovery and geothermal power generation.
Electrolyte Additive In the electronics industry, it is used as a functional additive in lithium-ion battery electrolytes to improve thermal stability and enhance the cycling performance of high-voltage cells.
Packaging
Standard industrial packaging options for 2,2,2-Trifluoroethanol include:
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25kg or 50kg HDPE plastic drums or specialized fluorinated containers.
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250kg stainless steel or lined steel drums for high-volume industrial use.
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ISO Tanks available for bulk international distribution.
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Sealed glass bottles or small fluorinated canisters for laboratory-scale requirements.
Storage
2,2,2-Trifluoroethanol must be stored in a cool, dry, and well-ventilated warehouse. Containers must be kept tightly closed and stored in an area designated for flammable or toxic materials. Protect from direct sunlight and heat sources. Due to its reactivity, it should be kept away from strong oxidizing agents, strong bases, and alkali metals. Ensure that storage vessels are made of compatible materials like stainless steel or high-density fluorinated plastics.
